Panacea, Florida has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 14.6 °C (low) to 25.7 °C (high). Annual precipitation averages 1498.1 Millimeters. Panacea is located in USDA Plant Hardiness Zone 9a. The growing season typically runs from the last frost around Feb. 1 - Feb. 10 through the first frost around Dec. 21 - Dec. 31.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | 5.3 °C | 17.2 °C | 114.3 mm |
| February | 7 °C | 18.9 °C | 100.33 mm |
| March | 10.3 °C | 22.1 °C | 139.45 mm |
| April | 13.8 °C | 25.4 °C | 104.65 mm |
| May | 17.9 °C | 29.2 °C | 73.91 mm |
| June | 21.8 °C | 31.6 °C | 166.62 mm |
| July | 22.9 °C | 32.3 °C | 191.26 mm |
| August | 23.1 °C | 32.2 °C | 200.91 mm |
| September | 21.1 °C | 30.7 °C | 156.97 mm |
| October | 15.7 °C | 27.2 °C | 85.85 mm |
| November | 9.8 °C | 22.4 °C | 77.72 mm |
| December | 6.9 °C | 18.6 °C | 86.11 mm |
| Annual | 14.6 °C | 25.7 °C | 1498.08 mm |
| Average First Frost Date | Dec. 21 - Dec. 31 |
| Average Last Frost Date | Feb. 1 - Feb. 10 |
| Average Days With Frost | 10-20 Days |
| Plant Hardiness Zone | Zone 9a : -6.7°C to -3.9°C |
| Plant Hardiness Zone - 2012 | Zone 9a : -6.7°C to -3.9°C |
| Current Drought Conditions | Extreme Drought |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |