Prentiss, Mississippi has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 12.3 °C (low) to 25 °C (high). Annual precipitation averages 1522.2 Millimeters. Prentiss is located in USDA Plant Hardiness Zone 8b. The growing season typically runs from the last frost around Mar. 1 - Mar. 10 through the first frost around Nov. 11 - Nov. 20.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | 2.7 °C | 14.9 °C | 145.03 mm |
| February | 4.3 °C | 17.3 °C | 143.51 mm |
| March | 7.8 °C | 21.3 °C | 142.24 mm |
| April | 11.7 °C | 25.1 °C | 140.72 mm |
| May | 16.3 °C | 28.9 °C | 109.98 mm |
| June | 20.3 °C | 32.1 °C | 129.29 mm |
| July | 21.6 °C | 33.2 °C | 133.86 mm |
| August | 21.3 °C | 33.2 °C | 126.24 mm |
| September | 18.6 °C | 30.9 °C | 100.33 mm |
| October | 12.1 °C | 26.2 °C | 96.77 mm |
| November | 6.6 °C | 20.3 °C | 110.24 mm |
| December | 3.8 °C | 16.1 °C | 144.02 mm |
| Annual | 12.3 °C | 25 °C | 1522.23 mm |
| Average First Frost Date | Nov. 11 - Nov. 20 |
| Average Last Frost Date | Mar. 1 - Mar. 10 |
| Average Days With Frost | 30-40 Days |
| Plant Hardiness Zone | Zone 8b : -9.4°C to -6.7°C |
| Plant Hardiness Zone - 2012 | Zone 8b : -9.4°C to -6.7°C |
| Current Drought Conditions | Normal |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |