Sikeston, Missouri has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 9.1 °C (low) to 20.3 °C (high). Annual precipitation averages 1273.5 Millimeters. Sikeston is located in USDA Plant Hardiness Zone 7b. The growing season typically runs from the last frost around Mar. 21 - Mar. 31 through the first frost around Nov. 1 - Nov. 10.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | -2.7 °C | 6.2 °C | 91.19 mm |
| February | -1.2 °C | 9 °C | 98.55 mm |
| March | 3.3 °C | 14.5 °C | 118.87 mm |
| April | 8.8 °C | 20.8 °C | 136.14 mm |
| May | 14.7 °C | 25.9 °C | 137.16 mm |
| June | 19.3 °C | 30.7 °C | 99.82 mm |
| July | 21.2 °C | 32.1 °C | 104.39 mm |
| August | 19.9 °C | 31.7 °C | 76.45 mm |
| September | 15.3 °C | 28.3 °C | 88.9 mm |
| October | 8.7 °C | 22.1 °C | 98.04 mm |
| November | 3.2 °C | 14.2 °C | 112.78 mm |
| December | -0.8 °C | 8.1 °C | 111.25 mm |
| Annual | 9.1 °C | 20.3 °C | 1273.54 mm |
| Average First Frost Date | Nov. 1 - Nov. 10 |
| Average Last Frost Date | Mar. 21 - Mar. 31 |
| Average Days With Frost | 50-75 Days |
| Plant Hardiness Zone | Zone 7b : -15°C to -12.2°C |
| Plant Hardiness Zone - 2012 | Zone 7a : -17.8°C to -15°C |
| Current Drought Conditions | Normal |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |