Depew, Oklahoma has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 9.2 °C (low) to 22.2 °C (high). Annual precipitation averages 1014.5 Millimeters. Depew is located in USDA Plant Hardiness Zone 7b. The growing season typically runs from the last frost around Apr. 1 - Apr. 10 through the first frost around Nov. 1 - Nov. 10.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | -3.1 °C | 9.8 °C | 39.88 mm |
| February | -1.2 °C | 12.2 °C | 46.48 mm |
| March | 3.7 °C | 17.2 °C | 75.44 mm |
| April | 8.6 °C | 22.2 °C | 105.66 mm |
| May | 14.2 °C | 26.1 °C | 141.73 mm |
| June | 19.2 °C | 30.7 °C | 123.19 mm |
| July | 21.3 °C | 33.8 °C | 88.65 mm |
| August | 20.4 °C | 33.7 °C | 83.31 mm |
| September | 15.9 °C | 29.4 °C | 93.73 mm |
| October | 9.3 °C | 23.4 °C | 99.31 mm |
| November | 3.4 °C | 16.8 °C | 65.79 mm |
| December | -1.6 °C | 10.7 °C | 51.31 mm |
| Annual | 9.2 °C | 22.2 °C | 1014.48 mm |
| Average First Frost Date | Nov. 1 - Nov. 10 |
| Average Last Frost Date | Apr. 1 - Apr. 10 |
| Average Days With Frost | 75-100 Days |
| Plant Hardiness Zone | Zone 7b : -15°C to -12.2°C |
| Plant Hardiness Zone - 2012 | Zone 7a : -17.8°C to -15°C |
| Current Drought Conditions | Normal |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |