Mayo, South Carolina has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 9.4 °C (low) to 22.1 °C (high). Annual precipitation averages 1301 Millimeters. Mayo is located in USDA Plant Hardiness Zone 8a. The growing season typically runs from the last frost around Apr. 11 - Apr. 20 through the first frost around Oct. 21 - Oct. 31.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | -0.7 °C | 11.1 °C | 107.95 mm |
| February | 0.6 °C | 13.3 °C | 95.76 mm |
| March | 4.1 °C | 17.6 °C | 118.11 mm |
| April | 8.6 °C | 22.6 °C | 112.78 mm |
| May | 13.4 °C | 26.6 °C | 100.08 mm |
| June | 17.9 °C | 30.1 °C | 116.08 mm |
| July | 19.9 °C | 32.1 °C | 112.52 mm |
| August | 19.3 °C | 31 °C | 119.63 mm |
| September | 16.2 °C | 28.1 °C | 109.98 mm |
| October | 9.4 °C | 22.9 °C | 93.22 mm |
| November | 3.6 °C | 16.9 °C | 98.04 mm |
| December | 0.8 °C | 12.4 °C | 116.84 mm |
| Annual | 9.4 °C | 22.1 °C | 1300.99 mm |
| Average First Frost Date | Oct. 21 - Oct. 31 |
| Average Last Frost Date | Apr. 11 - Apr. 20 |
| Average Days With Frost | 75-100 Days |
| Plant Hardiness Zone | Zone 8a : -12.2°C to -9.4°C |
| Plant Hardiness Zone - 2012 | Zone 7b : -15°C to -12.2°C |
| Current Drought Conditions | Severe Drought |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |