Muleshoe, Texas has a Cold Semi-Arid Climate climate (Köppen classification: BSk). Average annual temperatures range from 5.6 °C (low) to 23 °C (high). Annual precipitation averages 462.5 Millimeters. Muleshoe is located in USDA Plant Hardiness Zone 7a. The growing season typically runs from the last frost around Apr. 11 - Apr. 20 through the first frost around Oct. 11 - Oct. 20.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | -5.5 °C | 11.8 °C | 11.43 mm |
| February | -3.9 °C | 14.4 °C | 10.67 mm |
| March | -0.1 °C | 18.9 °C | 23.37 mm |
| April | 3.9 °C | 23.3 °C | 25.15 mm |
| May | 9.9 °C | 27.6 °C | 50.29 mm |
| June | 15.6 °C | 32.6 °C | 71.63 mm |
| July | 17.6 °C | 33.2 °C | 63.25 mm |
| August | 16.8 °C | 32.6 °C | 69.34 mm |
| September | 12.7 °C | 28.7 °C | 60.2 mm |
| October | 5.8 °C | 23.4 °C | 43.94 mm |
| November | -0.9 °C | 17.1 °C | 17.27 mm |
| December | -4.7 °C | 12.2 °C | 16 mm |
| Annual | 5.6 °C | 23 °C | 462.54 mm |
| Average First Frost Date | Oct. 11 - Oct. 20 |
| Average Last Frost Date | Apr. 11 - Apr. 20 |
| Average Days With Frost | 125-150 Days |
| Plant Hardiness Zone | Zone 7a : -17.8°C to -15°C |
| Plant Hardiness Zone - 2012 | Zone 7a : -17.8°C to -15°C |
| Current Drought Conditions | Extreme Drought |
| Köppen Climate Classification | BSk - Cold Semi-Arid Climate |