Manderson, Wyoming has a Cold Desert Climate climate (Köppen classification: BWk). Average annual temperatures range from -0.4 °C (low) to 15.9 °C (high). Annual precipitation averages 184.7 Millimeters. Manderson is located in USDA Plant Hardiness Zone 4b. The growing season typically runs from the last frost around May 1 - May 10 through the first frost around Sep. 21 - Sep. 30.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | -14.8 °C | -0.9 °C | 6.1 mm |
| February | -11.7 °C | 2.8 °C | 6.6 mm |
| March | -5.2 °C | 10.6 °C | 8.13 mm |
| April | -0.1 °C | 15.9 °C | 18.8 mm |
| May | 5.7 °C | 21.3 °C | 35.81 mm |
| June | 10.3 °C | 27.5 °C | 27.69 mm |
| July | 13.6 °C | 32.7 °C | 14.48 mm |
| August | 11.8 °C | 31.7 °C | 8.89 mm |
| September | 6.4 °C | 25.3 °C | 24.89 mm |
| October | -0.1 °C | 16.4 °C | 18.8 mm |
| November | -7.2 °C | 7.2 °C | 8.64 mm |
| December | -13.3 °C | 0.2 °C | 5.84 mm |
| Annual | -0.4 °C | 15.9 °C | 184.67 mm |
| Average First Frost Date | Sep. 21 - Sep. 30 |
| Average Last Frost Date | May 1 - May 10 |
| Average Days With Frost | 150-180 Days |
| Plant Hardiness Zone | Zone 4b : -31.7°C to -28.9°C |
| Plant Hardiness Zone - 2012 | Zone 4a : -34.4°C to -31.7°C |
| Current Drought Conditions | Extreme Drought |
| Köppen Climate Classification | BWk - Cold Desert Climate |