Desoto Lakes, Florida has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 64.1 °F (low) to 83 °F (high). Annual precipitation averages 54.9 Inches. Desoto Lakes is located in USDA Plant Hardiness Zone 10a.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | 51.2 °F | 72.1 °F | 2.73 in. |
| February | 53.9 °F | 74.6 °F | 2.19 in. |
| March | 57.5 °F | 77.9 °F | 3.25 in. |
| April | 62.5 °F | 82.6 °F | 2.81 in. |
| May | 68.0 °F | 87.6 °F | 3.03 in. |
| June | 72.8 °F | 90.3 °F | 8.33 in. |
| July | 74.0 °F | 91.2 °F | 8.18 in. |
| August | 74.5 °F | 91.4 °F | 9.42 in. |
| September | 73.1 °F | 89.8 °F | 7.71 in. |
| October | 67.5 °F | 85.5 °F | 3.05 in. |
| November | 59.4 °F | 78.9 °F | 1.81 in. |
| December | 54.4 °F | 74.4 °F | 2.43 in. |
| Annual | 64.1 °F | 83 °F | 54.94 in. |
| Average First Frost Date | Frost Rare |
| Average Last Frost Date | |
| Average Days With Frost | Frost Free |
| Plant Hardiness Zone | Zone 10a : 30°F to 25°F |
| Plant Hardiness Zone - 2012 | Zone 9b : 25°F to 20°F |
| Current Drought Conditions | Extreme Drought |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |