Manasota Key, Florida has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 66.3 °F (low) to 80.2 °F (high). Annual precipitation averages 51.6 Inches. Manasota Key is located in USDA Plant Hardiness Zone 10b.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | 53.8 °F | 70.2 °F | 2.77 in. |
| February | 56.3 °F | 71.7 °F | 2.25 in. |
| March | 59.7 °F | 74.7 °F | 3.28 in. |
| April | 64.8 °F | 78.9 °F | 2.62 in. |
| May | 70.0 °F | 83.5 °F | 3.04 in. |
| June | 74.5 °F | 86.6 °F | 7.05 in. |
| July | 75.8 °F | 88.2 °F | 7.69 in. |
| August | 76.2 °F | 88.4 °F | 8.48 in. |
| September | 74.6 °F | 87.2 °F | 7.14 in. |
| October | 70.0 °F | 83.6 °F | 3.26 in. |
| November | 62.1 °F | 77.1 °F | 1.74 in. |
| December | 57.3 °F | 72.8 °F | 2.25 in. |
| Annual | 66.3 °F | 80.2 °F | 51.57 in. |
| Average First Frost Date | No Frost |
| Average Last Frost Date | |
| Average Days With Frost | Frost Free |
| Plant Hardiness Zone | Zone 10b : 35°F to 30°F |
| Plant Hardiness Zone - 2012 | Zone 10a : 30°F to 25°F |
| Current Drought Conditions | Normal |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |