Matlacha, Florida has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 66.8 °F (low) to 82.2 °F (high). Annual precipitation averages 56.2 Inches. Matlacha is located in USDA Plant Hardiness Zone 10b.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | 54.7 °F | 72.2 °F | 2.3 in. |
| February | 57.1 °F | 74.4 °F | 1.93 in. |
| March | 60.5 °F | 77.2 °F | 2.3 in. |
| April | 65.6 °F | 81.5 °F | 2.25 in. |
| May | 70.4 °F | 85.6 °F | 3.53 in. |
| June | 74.8 °F | 88.4 °F | 9.81 in. |
| July | 76.0 °F | 89.6 °F | 9.01 in. |
| August | 76.2 °F | 90.0 °F | 9.36 in. |
| September | 75.1 °F | 88.8 °F | 8.5 in. |
| October | 70.6 °F | 85.0 °F | 3.31 in. |
| November | 62.8 °F | 78.9 °F | 1.87 in. |
| December | 58.0 °F | 74.6 °F | 1.99 in. |
| Annual | 66.8 °F | 82.2 °F | 56.16 in. |
| Average First Frost Date | No Frost |
| Average Last Frost Date | |
| Average Days With Frost | Frost Free |
| Plant Hardiness Zone | Zone 10b : 35°F to 30°F |
| Plant Hardiness Zone - 2012 | Zone 10a : 30°F to 25°F |
| Current Drought Conditions | Normal |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |