Mayo, Florida has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 57 °F (low) to 80.1 °F (high). Annual precipitation averages 53.9 Inches. Mayo is located in USDA Plant Hardiness Zone 9a. The growing season typically runs from the last frost around Mar. 1 - Mar. 10 through the first frost around Nov. 21 - Nov. 30.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | 40.8 °F | 65.5 °F | 4.58 in. |
| February | 43.6 °F | 68.9 °F | 3.37 in. |
| March | 48.5 °F | 74.8 °F | 4.28 in. |
| April | 55.1 °F | 80.4 °F | 3.03 in. |
| May | 62.4 °F | 87.0 °F | 3.14 in. |
| June | 69.9 °F | 90.3 °F | 6.89 in. |
| July | 71.9 °F | 91.4 °F | 7.4 in. |
| August | 72.1 °F | 90.9 °F | 7.71 in. |
| September | 68.5 °F | 88.5 °F | 5.26 in. |
| October | 58.9 °F | 82.1 °F | 2.92 in. |
| November | 48.6 °F | 74.0 °F | 2.05 in. |
| December | 43.5 °F | 67.8 °F | 3.3 in. |
| Annual | 57 °F | 80.1 °F | 53.93 in. |
| Average First Frost Date | Nov. 21 - Nov. 30 |
| Average Last Frost Date | Mar. 1 - Mar. 10 |
| Average Days With Frost | 20-30 Days |
| Plant Hardiness Zone | Zone 9a : 20°F to 25°F |
| Plant Hardiness Zone - 2012 | Zone 8b : 15°F to 20°F |
| Current Drought Conditions | Extreme Drought |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |